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David Lab Alumni

Past Member name, Degree, Affiliation / Year Graduated or Departed;

Dissertation / Thesis Title

UC Davis

Alan Raetz, Ph.D., Biochemistry & Molecular Biology: Postdoctoral Researcher / 2019, Graduate Student / 2013

Ph.D. Dissertation: The Role of MUTYH in Oxidative DNA Damage Repair and Alkylative DNA Damage Response in Mammalian Cells

Doug Banda, Ph.D., Chemistry: Graduate Student / 2018

A Balancing Act: DNA Glycosylases & the DNA Damage Response to Alkylating Agents

Brittany Anderson-Steele, Ph.D., Chemistry: Graduate Student / 2018

Novel Substrates Are Differentially Processed by the Two Isoforms of the Base Excision Repair Glycosylase NEIL1

Nicole N. Nuñez, Ph.D., Chemistry: Graduate Student / 2018

The Base Excision Repair Glycosylase MUTYH Relies on Two Metallocofactors to Mitigate DNA Damage

Kori Lay, M.S., Chemistry: Graduate Student / 2018

Use of a Fluorescent RNA-Based Biosensor to Evaluate Methylthioadenosine Nucelosidase Inhibition by Transition State Analogs

Amelia Manlove, Ph.D., Chemistry: Graduate Student / 2017

Structure-Activity Relationships Reveal the Hidden Substrate Recognition Requirements of MutY Adenine DNA Glycosylase

Michael Burnside, M.S., Chemistry: Graduate Student / 2017

Use of Alternative Nucleophiles in the Base Excision Repair Mechanism

Phil Yuen, Ph.D., Chemistry: Graduate Student / 2016

The Development of Pyrrolidine Transition State Analogs as Chemical Probes for DNA Glycosylases

JohnPatrick Rogers, Ph.D., Chemistry: Graduate Student / 2016

Creating a Chemical Toolbox: The Chemical Synthesis of Modified Nucleotides as Probes of DNA Repair Glycosylases

Ryan Woods, Ph.D., Chemistry: Graduate Student / 2014

Investigation of the MutY Glycosylase Mechanism

Jongchan Yeo, Ph.D., Chemistry: Graduate Student / 2014

RNA Editing Changes the Lesion Specificity for the DNA Repair Enzyme hNEIL1

Paige McKibbin, Ph.D., Chemistry: Graduate Student / 2012

Base Excision Repair (BER) and Nucleotide Excision Repair (NER) of Both Natural and Synthetic Nucleotides

Megan Brinkmeyer, Ph.D., Chemistry: Graduate Student / 2012

Mismatch Recognition and Base Excision Repair of Natural and Unnatural Amino Acid Variations of the Adenine DNA Glycosylases, MutY and MUTYH

Lisa Engstrom, Ph.D., Chemistry: Graduate Student / 2011

Characterization of the Functional Significance of metal cofactors in DNA repair enzymes

Chen Gu, M.S., Chemistry: Graduate Student / 2011

Application of Surface Entropy Reduction Technique to the DNA Glycosylase MutY

University of Utah

Sheng Cao, Ph.D., Chemistry: Graduate Student / 2010

Synthesis of Fluorinated Analogs of Oxidative DNA Lesions and their Use to Probe Features of Recognition and Repair by Base Excision Repair Glycosylases

Aaron Fleming, Ph.D., Chemistry: Graduate Student / 2009

Reactivity of 8-Oxoguanosine

Valerie O’Shea, Ph.D., Chemistry: Graduate Student / 2009

The Use of Synthetic DNA Analogs for Investigating the Structure, Mechanism, and in vivo Repair of Mismatched DNA by MutY Adenine Glycosylase

Sucharita Kundu, Ph.D., Chemistry: Graduate Student / 2009

MUTYH-Mediated Repair of Oxidative DNA Damage: Functional Characterization and Investigation into Post-Translational Modifications of MUTYH and Variants Implicated in Colon Cancer

Nirmala Krishnamurthy, Ph.D., Chemistry: Graduate Student / 2008

Insight into the Role of Base Excision Repair in the Mutagenic Profile of Oxidized Guanines: Kinetics, Binding assays and in vivo Mutagenesis Experiments.

Jody Richards, M.S., Chemistry: Graduate Student / 2008

Recognition and Repair of DNA Damage by Bacterial Adenine Glycosylases

Alison Livingston, Ph.D., Chemistry: Graduate Student / 2006

Repair of DNA Damage by MYH and Variants Associated with Colorectal Cancer

Aym Berges, Ph.D., Chemistry: Graduate Student / 2006

In Vitro Polymerase Activity of Oxidized DNA Lesions with Wild-Type HIV-1 Reverse Transcriptase and Various Drug-Resistant Mutants

Olga Lukianova, Ph.D., Chemistry: Graduate Student / 2005

Repair of Damaged DNA by Iron-sulfur cluster-containing DNA Glycosylases

Mary Pope, Ph.D., Chemistry: Graduate Student / 2004

Repair of Mismatched DNA by Bacterial and Mammalian Adenine DNA Glycosylases

Anthony Francis, Ph.D., Chemistry: Graduate Student / 2003

Recognition and Catalysis of the DNA Repair Enzyme MutY

Michael Leipold, Ph.D., Chemistry: Graduate Student / 2003

The Recognition and Repair of Oxidized Guanine Species by Bacterial and Eukaryotic OG Glycosylases

Olga Kornyushyna, Ph.D., Chemistry: Graduate Student / 2002

In Vitro Polymerase Activity of Oxidized Guanosine Lesions Spiroiminodihydantoin and Guanidinohydantoin

Nikolas Chmiel, Ph.D., Chemistry: Graduate Student / 2002

Mutations Affecting the Structure and Catalytic Activity of the DNA Repair Enzyme MutY

Wenchen Luo, Ph.D., Chemistry: Graduate Student / 2001

Characterization of Purine Oxidation Products from One-Electron Oxidants, Superoxide and Singlet Oxygen

Marie-Pierre Golinelli-Cohen: Faculty Intern / 2001

Scott Williams, Ph.D., Chemistry: Graduate Student / 2000

Active Site Chemistry of the E. coli DNA Repair Adenine Glycosylase MutY

Cindy Chepanoske, Ph.D., Chemistry: Graduate Student / 2000

Substrate Recognition by the E. coli DNA Repair Enzyme MutY

Robyn Hickerson, Ph.D., Chemistry: Graduate Student / 2000

Transition Metal-Mediated Oxidation of Nucleic Acids: Applications to Structural Probing, 8-OxoG Detection, and Protein-DNA Cross-Linking

Daren Heaton, Ph.D., Biochemistry: Graduate Student / 2000

Biophysical Characterization of COX-17, the Metallochaperone to the Mitochondria

Michael Langer, M.S., Chemistry: Graduate Student / 1999

Evidence for a Critical Role of the Iron-Sulfur Cluster Loop Domain of E. coli MutY in DNA Damage Recognition and DNA Repair

Silvia Porello, Ph.D., Chemistry: Graduate Student / 1999

DNA Repair Enzyme MutY: Substrate Recognition Properties and Kinetics of Adenine Glycosylase Activity

Amber Podoll, M.S., Chemistry: Graduate Student / 1998

Investigation into the Unusual Structural Properties of the Repetitive Centromeric Sequences of Humans and Yeast

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Contact:

Dr. Sheila S. David
ssdavid@ucdavis.edu
(530)-752-4280

Department of Chemistry
One Shields Ave.
Davis, CA 95616