Home » Jonathan Lin

Jonathan Lin

Jonathan Lin

LinkedIn

Education:

B.S. Chemical biology, B.A. Music, UC Berkeley 2017

From:  San Jose, CA

Joined the David Lab: January 2018

Outside of lab: Music and the ergometer

 

 

Research in the David Lab

Oxidative damage to DNA can cause genetic mutations that lead to cancer. A lack of activity by DNA repair enzymes such as glycosylases deters the removal of these damaged DNA base pairs. Using synthetic methods, I develop nucleoside/nucleotide analogues that will serve as inhibitors of various DNA glycosylases. Doing so will allow us to “trap” these enzymes in action, in vitro and potentially in vivo, for structural and enzymatic studies. In addition, these analogues may be used to help develop pharmaceuticals to fight cancer.

Previous Research Experience:

As a visiting researcher in Dr. Ken Wong’s lab at the National Cheng-Kung University Medical School (Tainan, Taiwan), I sought after a non-invasive method to detect the onset of squamous cell carcinoma in dystrophic epidermolysis bullosa patients through analysis of patients’ wound fluids.

 

 

RSS Science Daily News

  • How 3D printers can give robots a soft touch April 17, 2024
    Soft skin coverings and touch sensors have emerged as a promising feature for robots that are both safer and more intuitive for human interaction, but they are expensive and difficult to make. A recent study demonstrates that soft skin pads doubling as sensors made from thermoplastic urethane can be efficiently manufactured using 3D printers.
  • Honey bees experience multiple health stressors out-in-the-field April 17, 2024
    It's not a single pesticide or virus stressing honey bees, and affecting their health, but exposure to a complex web of multiple interacting stressors encountered while at work pollinating crops, found new research. Scientists have been unable to explain increasing colony mortality, even after decades of research examining the role of specific pesticides, parasitic mites, […]
  • First evidence of human occupation in lava tube cave in Saudi Arabia April 17, 2024
    New research has highlighted an area in Arabia that once acted as a key point for cultural exchanges and trades amongst ancient people -- and it all took place in vast caves and lava tubes that have remained largely untapped reservoirs of archaeological abundance in Arabia. Through meticulous excavation and analysis, the international team uncovered […]
  • Paleontologists unearth what may be the largest known marine reptile April 17, 2024
    The fossilized remains of a second gigantic jawbone measuring more than two meters long has been found on a beach in Somerset, UK.
  • 38 trillion dollars in damages each year: World economy already committed to income reduction of 19 % due to climate change April 17, 2024
    Even if CO2 emissions were to be drastically cut down starting today, the world economy is already committed to an income reduction of 19% until 2050 due to climate change, a new study finds. These damages are six times larger than the mitigation costs needed to limit global warming to two degrees. Based on empirical […]

Contact:

Dr. Sheila S. David
ssdavid@ucdavis.edu
(530)-752-4280

Department of Chemistry
One Shields Ave.
Davis, CA 95616