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Jonathan Lin

Jonathan Lin

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Education:

B.S. Chemical biology, B.A. Music, UC Berkeley 2017

From:  San Jose, CA

Joined the David Lab: January 2018

Outside of lab: Music and the ergometer

 

 

Research in the David Lab

Oxidative damage to DNA can cause genetic mutations that lead to cancer. A lack of activity by DNA repair enzymes such as glycosylases deters the removal of these damaged DNA base pairs. Using synthetic methods, I develop nucleoside/nucleotide analogues that will serve as inhibitors of various DNA glycosylases. Doing so will allow us to “trap” these enzymes in action, in vitro and potentially in vivo, for structural and enzymatic studies. In addition, these analogues may be used to help develop pharmaceuticals to fight cancer.

Previous Research Experience:

As a visiting researcher in Dr. Ken Wong’s lab at the National Cheng-Kung University Medical School (Tainan, Taiwan), I sought after a non-invasive method to detect the onset of squamous cell carcinoma in dystrophic epidermolysis bullosa patients through analysis of patients’ wound fluids.

 

 

RSS Science Daily News

  • Plant-derived secondary organic aerosols can act as mediators of plant-plant interactions September 13, 2024
    A new study reveals that plant-derived secondary organic aerosols (SOAs) can act as mediators of plant-plant interactions. This research was conducted through the cooperation of chemical ecologists, plant ecophysiologists and atmospheric physicists.
  • Folded or cut, this lithium-sulfur battery keeps going September 13, 2024
    Most rechargeable batteries that power portable devices, such as toys, handheld vacuums and e-bikes, use lithium-ion technology. But these batteries can have short lifetimes and may catch fire when damaged. To address stability and safety issues, researchers have designed a lithium-sulfur (Li-S) battery that features an improved iron sulfide cathode. One prototype remains highly stable […]
  • Bacteria work together to thrive in difficult conditions September 13, 2024
    In a new study, researchers have determined through both statistical analysis and in experiments that soil pH is a driver of microbial community composition -- but that the need to address toxicity released during nitrogen cycling ultimately shapes the final microbial community.
  • Ignore antifungal resistance in fungal disease at your peril, warn top scientists September 13, 2024
    Without immediate action, humanity will potentially face further escalation in resistance in fungal disease, a group of scientists from the around the world has warned. According to the scientists most fungal pathogens identified by the World Health Organization -- accounting for around 3.8 million deaths a year -- are either already resistant or rapidly acquiring […]
  • Discovery could lead to longer-lasting EV batteries, hasten energy transition September 12, 2024
    Researchers have discovered why lithium-ion batteries, which power most electronic devices, lose capacity overtime. The findings could enable the development of electric vehicles that go far longer without needing a charge.

Contact:

Dr. Sheila S. David
ssdavid@ucdavis.edu
(530)-752-4280

Department of Chemistry
One Shields Ave.
Davis, CA 95616