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Mo Hashemian

Mo Hashemian

Education: B.S. Biological Sciences, University of California, Irvine, 2019 

From: Irvine, California

Joined David Lab: January 2021

Outside of lab: working out, watching TV

Research in David Lab:

In the lab, I utilize techniques in molecular and structural biology, protein biochemistry and enzymology. These skills were cultivated and applied in the process of solving the first full-length structure of an important human base excision repair glycosylase, MUTYH. This work has enabled us to characterize many functional features of the enzyme but has raised additional questions pertaining to the coordination of a zinc ion which is missing from the structure. My current work involves characterizing the structural motif that binds zinc, as well as characterizing naturally occurring cancer variants surrounding this motif. Our structure of MUTYH has also informed a second project, involving the potential discovery of a small molecule inhibitor that binds to a C-terminal substrate recognition motif, thereby diminishing enzymatic activity.

RSS Science Daily News

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  • How artificial intelligence could automate genomics research December 2, 2024
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  • Evidence of primordial black holes may be hiding in planets, or even everyday objects here on Earth December 2, 2024
    A theoretical study suggests that small black holes born in the early universe may have left behind hollow planetoids and microscopic tunnels, and that we should start looking within rocks and old buildings for them. The research proposes thinking both big and small to confirm the existence of primordial black holes, suggesting that their signatures […]
  • Temporary tattoo printed directly on the scalp offers easy, hair-friendly solution for measuring brainwaves December 2, 2024
    Scientists have invented a liquid ink that doctors can print onto a patient's scalp to measure brain activity. The technology offers a promising alternative to the cumbersome process currently used for monitoring brainwaves and diagnosing neurological conditions. It also has the potential to enhance non-invasive brain-computer interface applications.

Contact:

Dr. Sheila S. David
ssdavid@ucdavis.edu
(530)-752-4280

Department of Chemistry
One Shields Ave.
Davis, CA 95616