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We bid you adieu, Holly Vickery!
David Lab researcher Holly Vickery is off to graduate school, and the David Lab wishes her farewell. Holly worked on multiple projects as a research scientist in the David Lab. One project was focused on measuring the cellular repair efficiency of MutY variants, while another project revolved around optimizing a purification technique of MUTYH for higher yields […]
New Manuscript Published: Selective base excision repair of DNA damage by the non‐base‐flipping DNA glycosylase AlkC.
New Manuscript Published: Selective base excision repair of DNA damage by the non‐base‐flipping DNA glycosylase AlkC. The preservation of genomic integrity performed by DNA repair machinery is crucial for living organisms, and malfunctions in DNA repair machinery can have far-reaching and devastating effects on a cell’s ability to attain precise DNA replication, properly regulate cell […]
David Lab Graduate Student Spotlight: Nicole N. Nuñez
8/28/2017 Presenting the David Lab Graduate Student Spotlight, featuring Nicole Nuñez. We discuss with Nicole how she found her way onto the STEM pathway she is currently traveling as she is completing her Ph.D, and Nicole details the powerful motivation behind her passion for investigating the mechanisms of cancer, and how her path helped lead […]
Best Wishes to David Lab researchers Taylor, Jazmin, and Beili!
8/11/2017 As summer continues to roll on, and summer REU’s are approaching their completion, we have to say goodbye to our summer REU researchers Jazmin and Beili, and to recently graduated David Lab researchers like Taylor who are moving on to graduate school. →Taylor McCart, who recently graduated from UC Davis with a B.S. in […]
Farewell Young Scholar Garrett Ma!
8/4/2017 Garrett has spent the summer in the David Lab conducting advanced research alongside graduate student lab members Nicole and Cindy as part of the UC Davis Young Scholars Program. Even good things come to an end, and in following with David Lab tradition, Garrett leaves his mark before saying goodbye. We wish Garrett the […]
Just Accepted Manuscript: Structure Activity Relationships Reveal Key Features of 8-Oxoguanine:Adenine Mismatch Detection by the MutY DNA Glycosylase
7/20/2017 The recently accepted manuscript, Structure Activity Relationships Reveal Key Features of 8-Oxoguanine:Adenine Mismatch Detection by the MutY DNA Glycosylase, was accepted for publication in ACS Chemical Biology. MutY, remarkably, is able to specifically recognize and initiate repair of target OG:A mismatches from among a vast sea of natural DNA. To help reveal molecular features of […]
Just Accepted Manuscript: S K-edge XAS Studies of the Effect of DNA Binding on the [Fe4S4] Site in EndoIII and MutY
7/18/2017 Check out the latest manuscript from the David Lab and collaborators: S K-edge XAS Studies of the Effect of DNA Binding on the [Fe4S4] Site in EndoIII and MutY, which was recently accepted for publication in JACS. In this work, the iron-sulfur clusters of DNA repair glycosylases Endonuclease III and MutY were examined using S K-edge […]
Dare to Repair with Nicole Nuñez
6/6/2017 Take a walk with Nicole Nuñez as she illustrates how the David Lab investigates DNA repair.
Science Daily News
- The bright yellow worm that turns ocean poison into golden survival crystals August 27, 2025Deep beneath the Pacific Ocean, a bright yellow worm thrives where no other animals dare, in toxic hydrothermal vents saturated with arsenic and sulfide. By cleverly turning these poisons into a golden mineral once prized by Renaissance painters, the worm neutralizes the deadly threat and survives in one of Earth’s most hostile habitats. Scientists say […]
- The ancient oxygen flood that forever changed life in the oceans August 27, 2025Ancient forests may have fueled a deep-sea oxygen boost nearly 390 million years ago, unlocking evolutionary opportunities for jawed fish and larger marine animals. New isotopic evidence shows that this permanent oxygenation marked a turning point in Earth’s history — a reminder of how fragile the ocean’s oxygen balance remains today.
- Scientists just created spacetime crystals made of knotted light August 27, 2025Researchers have developed a blueprint for weaving hopfions—complex, knot-like light structures—into repeating spacetime crystals. By exploiting two-color beams, they can generate ordered chains and lattices with tunable topology, potentially revolutionizing data storage, communications, and photonic processing.
- Tiny hologram inside a fiber lets scientists control light with incredible precision August 27, 2025Researchers in Germany have unveiled the Metafiber, a breakthrough device that allows ultra-precise, rapid, and compact control of light focus directly within an optical fiber. Unlike traditional systems that rely on bulky moving parts, the Metafiber uses a tiny 3D nanoprinted hologram on a dual-core fiber to steer light by adjusting power between its cores. […]
- This tiny iron catalyst could transform the future of clean energy August 27, 2025Hydrogen fuel cells could power cars, devices, and homes with nothing but water as a byproduct—but platinum’s cost holds them back. Chinese researchers have now unveiled a breakthrough iron-based catalyst that could rival platinum while boosting efficiency and durability. With its clever “inner activation, outer protection” design, this new catalyst not only reduces harmful byproducts […]