David Lab Alumni
Past Member name, Degree: Affiliation / Year Graduated or Departed;
Dissertation / Thesis Title
UC Davis
Steven Merrill, Ph.D., Chemistry: Graduate Student / 2024
Exploration of DNA Glycosylase MutY Mode of DNA Traversing and Nucleotide Flipping
Joshua Bumgarner, Ph.D., Chemistry: Graduate Student / 2024
Not a Picky Glycosylase: Insights Into the NEIL Family of Glycosylases’ Activity as Impacted by DNA Lesions, Context and Crowding Agents
Selena Leu: Graduate Student / 2024
Dr. Carlos Trasviña-Arenas: Postdoctoral Scholar / 2023
Savannah Conlon, Ph.D., Chemistry: Graduate Student / 2023
The Role of MUTYH and NEIL in Cellular Repair of Oxidative DNA Damage
Robert Van Ostrand: Graduate Student / 2022
Merve Demir, Ph.D., Chemistry: Graduate Student / 2022
Mutational, Biochemical and Structural Studies of MutY Residues in a Hydrogen Bond Network Reveal Their Significant Roles in OG Recognition, Base Flipping and Adenine Excision Mechanism
Nikole Tamayo, M.S., Chemistry: Graduate Student / 2022
Investigating the Role of the Iron-Sulfur Cluster in DNA Glycosylase MutY Enzymes: Structural and Biochemical Analyses of a Cancer Associated Variant and “Clusterless” Lactobacillus brevis MutY
Functional Characterization of Cancer-Associated Mutations in the Interdomain Connector in the Mammalian Homologs of the Adenine Glycosylase MUTYH
Elizabeth Lotsof, Ph.D., Chemistry: Graduate Student / 2021
Evaluating the Influence of DNA Damage Substrates and DNA Context on Recognition and Repair by the NEIL Family of DNA Repair Enzymes
Jonathan Lin, M.S., Chemistry: Graduate Student / 2020
Site Directed Mutagenesis, Alternative Nucleophiles, and Transition-state Analogues Reveal New Features of the MutY Glycosylase Active Site
Chandrima Majumdar, Ph.D., Chemistry: Graduate Student / 2020
Molecular Insights into Damage Sensing by the DNA Repair Enzyme MutY
Dr. Alan Raetz: Postdoctoral Scholar / 2019
Doug Banda, Ph.D., Chemistry: Graduate Student / 2018
A Balancing Act: DNA Glycosylases & the DNA Damage Response to Alkylating Agents
Brittany Anderson-Steele, Ph.D., Chemistry: Graduate Student / 2018
Novel Substrates Are Differentially Processed by the Two Isoforms of the Base Excision Repair Glycosylase NEIL1
Nicole N. Nuñez, Ph.D., Chemistry: Graduate Student / 2018
The Base Excision Repair Glycosylase MUTYH Relies on Two Metallocofactors to Mitigate DNA Damage
Kori Lay, M.S., Chemistry: Graduate Student / 2018
Use of a Fluorescent RNA-Based Biosensor to Evaluate Methylthioadenosine Nucelosidase Inhibition by Transition State Analogs
Amelia Manlove, Ph.D., Chemistry: Graduate Student / 2017
Structure-Activity Relationships Reveal the Hidden Substrate Recognition Requirements of MutY Adenine DNA Glycosylase
Michael Burnside, M.S., Chemistry: Graduate Student / 2017
Use of Alternative Nucleophiles in the Base Excision Repair Mechanism
Phil Yuen, Ph.D., Chemistry: Graduate Student / 2016
The Development of Pyrrolidine Transition State Analogs as Chemical Probes for DNA Glycosylases
JohnPatrick Rogers, Ph.D., Chemistry: Graduate Student / 2016
Creating a Chemical Toolbox: The Chemical Synthesis of Modified Nucleotides as Probes of DNA Repair Glycosylases
Ryan Woods, Ph.D., Chemistry: Graduate Student / 2014
Investigation of the MutY Glycosylase Mechanism
Jongchan Yeo, Ph.D., Chemistry: Graduate Student / 2014
RNA Editing Changes the Lesion Specificity for the DNA Repair Enzyme hNEIL1
Alan Raetz, Ph.D., Biochemistry & Molecular Biology: Graduate Student / 2013
The Role of MUTYH in Oxidative DNA Damage Repair and Alkylative DNA Damage Response in Mammalian Cells
Paige McKibbin, Ph.D., Chemistry: Graduate Student / 2012
Base Excision Repair (BER) and Nucleotide Excision Repair (NER) of Both Natural and Synthetic Nucleotides
Megan Brinkmeyer, Ph.D., Chemistry: Graduate Student / 2012
Mismatch Recognition and Base Excision Repair of Natural and Unnatural Amino Acid Variations of the Adenine DNA Glycosylases, MutY and MUTYH
Lisa Engstrom, Ph.D., Chemistry: Graduate Student / 2011
Characterization of the Functional Significance of metal cofactors in DNA repair enzymes
Chen Gu, M.S., Chemistry: Graduate Student / 2011
Application of Surface Entropy Reduction Technique to the DNA Glycosylase MutY
University of Utah
Sheng Cao, Ph.D., Chemistry: Graduate Student / 2010
Synthesis of Fluorinated Analogs of Oxidative DNA Lesions and their Use to Probe Features of Recognition and Repair by Base Excision Repair Glycosylases
Aaron Fleming, Ph.D., Chemistry: Graduate Student / 2009
Reactivity of 8-Oxoguanosine
Valerie O’Shea, Ph.D., Chemistry: Graduate Student / 2009
The Use of Synthetic DNA Analogs for Investigating the Structure, Mechanism, and in vivo Repair of Mismatched DNA by MutY Adenine Glycosylase
Sucharita Kundu, Ph.D., Chemistry: Graduate Student / 2009
MUTYH-Mediated Repair of Oxidative DNA Damage: Functional Characterization and Investigation into Post-Translational Modifications of MUTYH and Variants Implicated in Colon Cancer
Nirmala Krishnamurthy, Ph.D., Chemistry: Graduate Student / 2008
Insight into the Role of Base Excision Repair in the Mutagenic Profile of Oxidized Guanines: Kinetics, Binding assays and in vivo Mutagenesis Experiments.
Jody Richards, M.S., Chemistry: Graduate Student / 2008
Recognition and Repair of DNA Damage by Bacterial Adenine Glycosylases
Alison Livingston, Ph.D., Chemistry: Graduate Student / 2006
Repair of DNA Damage by MYH and Variants Associated with Colorectal Cancer
Aym Berges, Ph.D., Chemistry: Graduate Student / 2006
In Vitro Polymerase Activity of Oxidized DNA Lesions with Wild-Type HIV-1 Reverse Transcriptase and Various Drug-Resistant Mutants
Olga Lukianova, Ph.D., Chemistry: Graduate Student / 2005
Repair of Damaged DNA by Iron-sulfur cluster-containing DNA Glycosylases
Mary Pope, Ph.D., Chemistry: Graduate Student / 2004
Repair of Mismatched DNA by Bacterial and Mammalian Adenine DNA Glycosylases
Anthony Francis, Ph.D., Chemistry: Graduate Student / 2003
Recognition and Catalysis of the DNA Repair Enzyme MutY
Michael Leipold, Ph.D., Chemistry: Graduate Student / 2003
The Recognition and Repair of Oxidized Guanine Species by Bacterial and Eukaryotic OG Glycosylases
Olga Kornyushyna, Ph.D., Chemistry: Graduate Student / 2002
In Vitro Polymerase Activity of Oxidized Guanosine Lesions Spiroiminodihydantoin and Guanidinohydantoin
Nikolas Chmiel, Ph.D., Chemistry: Graduate Student / 2002
Mutations Affecting the Structure and Catalytic Activity of the DNA Repair Enzyme MutY
Wenchen Luo, Ph.D., Chemistry: Graduate Student / 2001
Characterization of Purine Oxidation Products from One-Electron Oxidants, Superoxide and Singlet Oxygen
Marie-Pierre Golinelli-Cohen: Faculty Intern / 2001
Scott Williams, Ph.D., Chemistry: Graduate Student / 2000
Active Site Chemistry of the E. coli DNA Repair Adenine Glycosylase MutY
Cindy Chepanoske, Ph.D., Chemistry: Graduate Student / 2000
Substrate Recognition by the E. coli DNA Repair Enzyme MutY
Robyn Hickerson, Ph.D., Chemistry: Graduate Student / 2000
Transition Metal-Mediated Oxidation of Nucleic Acids: Applications to Structural Probing, 8-OxoG Detection, and Protein-DNA Cross-Linking
Daren Heaton, Ph.D., Biochemistry: Graduate Student / 2000
Biophysical Characterization of COX-17, the Metallochaperone to the Mitochondria
Michael Langer, M.S., Chemistry: Graduate Student / 1999
Evidence for a Critical Role of the Iron-Sulfur Cluster Loop Domain of E. coli MutY in DNA Damage Recognition and DNA Repair
Silvia Porello, Ph.D., Chemistry: Graduate Student / 1999
DNA Repair Enzyme MutY: Substrate Recognition Properties and Kinetics of Adenine Glycosylase Activity
Amber Podoll, M.S., Chemistry: Graduate Student / 1998
Investigation into the Unusual Structural Properties of the Repetitive Centromeric Sequences of Humans and Yeast
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